14 (S) -HDHA-d5
14 (S) -HDHA-d5 (14 (S) -HDoHE-d5) is deuterium labeled 14 (S) -HDHA. 14 (S) -HDHA (14 (S) -HDoHE) is an oxygenation product of Docosahexaenoic acid (DHA) . 14 (S) -HDHA is a marker reflecting activation of a Docosahexaenoic acid carbon 14-lipoxygenation pathway[1][2].
Product Specifications
Product Name Alternative
14 (S) -HDoHE-d5
UNSPSC
12352211
Target
Drug Metabolite; Isotope-Labeled Compounds
Type
Isotope-Labeled Compounds
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Neurological Disease
Smiles
O[C@H](/C=C/C=C\C/C=C\C/C=C\CCC(O)=O)C/C=C\C/C=C\C([2H])(C([2H])([2H])[2H])[2H]
Molecular Formula
C22H27D5O3
Molecular Weight
349.52
References & Citations
[1]Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019 Feb;53 (2) :211-216.|[2]Charles N Serhan, et al. Maresins: novel macrophage mediators with potent antiinflammatory and proresolving actions. J Exp Med. 2009 Jan 16;206 (1) :15-23.
Shipping Conditions
Room temperature
Scientific Category
Isotope-Labeled Compounds
Clinical Information
No Development Reported
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