(1S,2R) -1-Aminoindan-2-ol

(1S,2R) -1-Aminoindan-2-ol is a chiral resolving agent. (1S,2R) -1-Aminoindan-2-ol efficiently resolves various racemic 2-arylalkanoic acids and precisely controls the stereostructure of the products in asymmetric syntheses. (1S,2R) -1-Aminoindan-2-ol can be used in the synthesis of HIV protease inhibitors[1][2].

Product Specifications

CAS Number

[126456-43-7]

UNSPSC

12352200

Hazard Statement

H315, H319, H335

Target

Biochemical Assay Reagents

Type

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/1s-2r-1-aminoindan-2-ol.html

Purity

99.96

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O[C@H]1[C@@H](N)C2=C(C=CC=C2)C1

Molecular Formula

C9H11NO

Molecular Weight

149.19

Precautions

H315, H319, H335

References & Citations

[1]Kinbara K, et al. Chiral discrimination of 2-arylalkanoic acids by (1 S, 2 R) -1-aminoindan-2-ol through the formation of a consistent columnar supramolecular hydrogen-bond network. Journal of the Chemical Society, Perkin Transactions 2, 2000 (1) : 111-119. |[2]Ghosh AK, et al. Transition-State Mimetics for HIV Protease Inhibitors: Stereocontrolled Synthesis of Hydroxyethylene and Hydroxyethylamine Isosteres by Ester-Derived Titanium Enolate Syn and Anti-Aldol Reactions. J Org Chem. 1998 Sep 4;63 (18) :6146-6152.