Epothilone F
Epothilone F is a hydroxymethyl-thiazole analogue and active metabolite of Epothilone D. It acts as a microtubule-stabilizing agent with a mechanism similar to taxanes but with a simpler structure and improved aqueous solubility, eliminating the need for solubilizing agents like cremophor. It has demonstrated potent antitumor activity in both in vitro cell line studies and in vivo cancer models.
Product Specifications
CAS Number
208518-52-9
Field of Research
Signal Transduction
Smiles
C[C@@]12[C@@] (O1) (C[C@@H] (\C (=C\C=3N=C (CO) SC3) \C) OC (=O) C[C@H] (O) C (C) (C) C (=O) [C@H] (C) [C@@H] (O) [C@@H] (C) CCC2) [H]
Molecular Formula
C27H41NO7S
Molecular Weight
523.68
Storage Conditions
-20°C
Notes
For research use only.
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