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Epothilone F

Epothilone F is a hydroxymethyl-thiazole analogue and active metabolite of Epothilone D. It acts as a microtubule-stabilizing agent with a mechanism similar to taxanes but with a simpler structure and improved aqueous solubility, eliminating the need for solubilizing agents like cremophor. It has demonstrated potent antitumor activity in both in vitro cell line studies and in vivo cancer models.

Product Specifications

CAS Number

208518-52-9

Field of Research

Signal Transduction

Smiles

C[C@@]12[C@@] (O1) (C[C@@H] (\C (=C\C=3N=C (CO) SC3) \C) OC (=O) C[C@H] (O) C (C) (C) C (=O) [C@H] (C) [C@@H] (O) [C@@H] (C) CCC2) [H]

Molecular Formula

C27H41NO7S

Molecular Weight

523.68

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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