SNIPER (ABL) -38
SNIPER (ABL) -38 is a proteolysis-targeting chimera that induces the degradation of the BCR-ABL oncoprotein by recruiting inhibitor of apoptosis proteins (IAPs) . This tool compound is used in vitro and in vivo to study targeted protein degradation and chronic myeloid leukemia pathogenesis.
Product Specifications
Smiles
O=C (C1=CN=C (NC2=NC (C) =NC (N3CCN (C (COCCOCCOC4=CC=CC (C (C5=CSC ([C@H]6N (C ([C@H] (C7CCCCC7) NC ([C@@H] (NC) C) =O) =O) CCC6) =N5) =O) =C4) =O) CC3) =C2) S1) NC8=C (C) C=CC=C8Cl
Molecular Formula
C52H64ClN11O8S2
Molecular Weight
1070.72
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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