VU0456940
VU0456940 is a selective M1 muscarinic acetylcholine receptor positive allosteric modulator (PAM) . It potentiates cholinergic signaling in vitro, shifting cortical neuron APP processing toward the nonamyloidogenic pathway to increase sAPPα release. This compound is a valuable research tool for studying M1 receptor function in neurobiology and Alzheimer's disease-related models.
Product Specifications
Smiles
CN1N=CC (C2=CC=C (N3C=C (S (=O) (CC (CC4=NOC (C) =C4) =O) =O) C5=C3C=C (F) C=C5F) C=N2) =C1
Molecular Formula
C24H19F2N5O4S
Molecular Weight
511.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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