VU6010608
VU6010608 is a potent and brain-penetrant negative allosteric modulator (NAM) of the mGlu7 receptor. It effectively blocks long-term potentiation (LTP) induced by high-frequency stimulation in electrophysiological studies, making it a valuable research tool for investigating synaptic plasticity, neuropsychiatric disorders, and related in vitro and in vivo models.
Product Specifications
Smiles
O=C (NC1=CC (OC (F) (F) F) =CC=C1N2N=CN=C2) C3=CC=C (OC) C (OC) =C3
Molecular Formula
C18H15F3N4O4
Molecular Weight
408.34
Storage Conditions
-20°C
Notes
For research use only.
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