WZ4002-hydroxy
WZ4002-hydroxyl, a WZ4002 analogue with hydroxyl replacing methoxy, is identified in 50% of gefitinib- or erlotinib-resistant patients. WZ4002 features a distinct covalent pyrimidine scaffold. It is used in research on EGFR-driven cancers, including in vitro and in vivo studies of resistance mechanisms.
Product Specifications
Smiles
C=CC (NC1=CC=CC (OC2=NC (NC3=CC=C (C=C3O) N4CCN (CC4) C) =NC=C2Cl) =C1) =O
Molecular Formula
C24H25ClN6O3
Molecular Weight
480.95
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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