Cytostatin (sodium salt)
Cytostatin sodium salt is a potent and selective PP2A inhibitor (IC50 = 29 nM) that disrupts tumor cell adhesion and metastasis. It demonstrates antitumor activity by inhibiting B16 melanoma cell adhesion to laminin and collagen IV in vitro and reducing metastasis in mice, while also inducing apoptosis in fibrosarcoma cells.
Product Specifications
CAS Number
457070-06-3
Field of Research
Cell Biology, Metabolism Research
Smiles
[Na].[H][C@]1 (OC (=O) C=C[C@@H]1C) [C@@H] (C) CC[C@H] (OP (O) (O) =O) [C@@H] (C) [C@@H] (O) \C=C/C=C\C=C\C
Molecular Formula
C21H33NaO7P
Molecular Weight
451.452
Storage Conditions
Powder: -20°C for 3 years. In solvent: -80°C for 1 year.
Notes
For research use only.
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