Bongkrekic acid
Bongkrekic acid ammonium salt is a mitochondrial toxin from Burkholderia gladioli that potently inhibits adenine nucleotide translocase (ANT) . It is widely used in research to study mitochondrial dysfunction, apoptosis, and immune responses such as neutrophil extracellular trap (NET) formation, involving p38, ERK, PAD4, and P2X1 signaling pathways in vitro.
Product Specifications
CAS Number
11076-19-0
Field of Research
Cell Biology
Purity
>98%
Bioactivity
Mitochondrial permeability pore inhibitor
Form
Solution of 1mg/ml in Tris buffer
Solubility
Miscible with DMSO
Smiles
C (\C=C\[C@H] (C/C=C/CC/C=C/C=C\C[C@H] (/C (=C\C=C (\C (O) =O) /C) /C) OC) C) (/CC (O) =O) =C\C (O) =O
Molecular Formula
C28H38O7 (free acid)
Molecular Weight
486.6
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
3-Carboxymethyl-17-methoxy-6,18,21-trimethyldocosa-2,4,8,12,18,20-heptaenedioic acid
Available Sizes
Frequently Asked Questions
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