TBK1 control PROTAC 4

This compound serves as a negative control for the TBK1-targeting PROTAC 3i, exhibiting high-affinity binding to TBK1 without inducing its degradation. It is a critical tool for validating on-target PROTAC mechanisms in both cellular and biochemical studies of innate immunity and oncology research. PROTAC is a registered trademark of Arvinas Operations, Inc., and is used under license.

Product Specifications

CAS Number

2052306-31-5

Field of Research

Signal Transduction

Smiles

CN (CCCNc1nc (Nc2ccc (OCCCOCCCCOCCCOCC (=O) N[C@H] (C (=O) N3C[C@@H] (O) C[C@H]3C (=O) NCc3ccc (cc3) -c3scnc3C) C (C) (C) C) cc2) ncc1Br) C (=O) C1CCC1 |@@:57|