Becatecarin
Becatecarin is a water-soluble rebeccamycin analog that acts as a dual topoisomerase I/II inhibitor by intercalating DNA and stabilizing the topoisomerase-DNA complex, leading to DNA cleavage and apoptosis. Its anticancer and myelosuppressive effects have been studied in vivo, and it is a known substrate of the ABCG2 transporter.
Product Specifications
CAS Number
119673-08-4
Field of Research
Molecular Biology
Smiles
CCN (CC) CCN1C (=O) c2c (C1=O) c1c3cccc (Cl) c3n ([C@@H]3O[C@H] (CO) [C@@H] (OC) [C@H] (O) [C@H]3O) c1c1[nH]c3c (Cl) cccc3c21
Molecular Formula
C33H34Cl2N4O7
Molecular Weight
669.56
Storage Conditions
-20°C
Notes
For research use only.
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