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4-oxo Docosahexaenoic Acid

4-oxo Docosahexaenoic acid (4-oxo DHA) is a bioactive DHA metabolite that acts as a covalent PPARγ agonist, activating transcription with an EC50 of ~8-16 μM. It exhibits antiproliferative activity against multiple triple-negative breast cancer cell lines in vitro at 50-100 μM, while paradoxically stimulating MCF-7 cell growth, making it a compound of interest for cancer and metabolic research.

Product Specifications

CAS Number

845673-74-7

Field of Research

Metabolism Research, Molecular Biology

Smiles

CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C=C/C (=O) CCC (O) =O

Molecular Formula

C22H30O3

Molecular Weight

342.479

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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