4-oxo Docosahexaenoic Acid
4-oxo Docosahexaenoic acid (4-oxo DHA) is a bioactive DHA metabolite that acts as a covalent PPARγ agonist, activating transcription with an EC50 of ~8-16 μM. It exhibits antiproliferative activity against multiple triple-negative breast cancer cell lines in vitro at 50-100 μM, while paradoxically stimulating MCF-7 cell growth, making it a compound of interest for cancer and metabolic research.
Product Specifications
CAS Number
845673-74-7
Field of Research
Metabolism Research, Molecular Biology
Smiles
CC\C=C/C\C=C/C\C=C/C\C=C/C\C=C/C=C/C (=O) CCC (O) =O
Molecular Formula
C22H30O3
Molecular Weight
342.479
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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