(±) 4 (5) -DiHDPA lactone

(±) 5 (6) -DiHET lactone is a 1,5-cyclic ester derived from the epoxidation of arachidonic acid at the ω-5 bond. Its structural analog, (±) 4 (5) -DiHDPA lactone, is a 1,4-cyclic ester formed from epoxidized docosahexaenoic acid (DHA) at the ω-4 bond. These synthetic epoxy fatty acid lactones are research tools for studying lipid mediators in inflammation and vascular biology, though their specific biological roles remain under investigation.