12-oxo Leukotriene B4
12-Oxo Leukotriene B4 is a pro-inflammatory metabolite of LTB4 formed via the 12-hydroxydehydrogenase pathway. It is a key tool for studying the 5-lipoxygenase cascade and leukocyte activation, including neutrophil chemotaxis and calcium mobilization, in both in vitro and in vivo inflammation models. Its rapid conversion to less active dihydro metabolites is also a focus of eicosanoid inactivation research.
Product Specifications
CAS Number
136696-10-1
Field of Research
Metabolism Research
Smiles
C (=C\C=C\C=C\C (C/C=C\CCCCC) =O) \[C@H] (CCCC (O) =O) O
Molecular Formula
C20H30O4
Molecular Weight
334.45
Storage Conditions
-20°C
Notes
For research use only.
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