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12-oxo Leukotriene B4

12-Oxo Leukotriene B4 is a pro-inflammatory metabolite of LTB4 formed via the 12-hydroxydehydrogenase pathway. It is a key tool for studying the 5-lipoxygenase cascade and leukocyte activation, including neutrophil chemotaxis and calcium mobilization, in both in vitro and in vivo inflammation models. Its rapid conversion to less active dihydro metabolites is also a focus of eicosanoid inactivation research.

Product Specifications

CAS Number

136696-10-1

Field of Research

Metabolism Research

Smiles

C (=C\C=C\C=C\C (C/C=C\CCCCC) =O) \[C@H] (CCCC (O) =O) O

Molecular Formula

C20H30O4

Molecular Weight

334.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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