Amyloid-β (1-8, A2V) Peptide

The Aβ40 A2V peptide is a pathogenic variant that accelerates amyloid fibril formation in vitro and elevates Aβ levels in cellular models. This mutation is linked to early-onset Alzheimer's disease in homozygous carriers, making it a critical tool for studying amyloid aggregation mechanisms and genetic factors in neurodegeneration research.