11 (R) -HEPE

This specialized oxylipin is biosynthesized from eicosapentaenoic acid (EPA) via the enzymatic action of 11 (R) -lipoxygenase, originally characterized in the sea urchin Strongylocentrotus purpuratus. It serves as a valuable research tool for studying inflammation resolution, specialized pro-resolving mediator (SPM) pathways, and eicosanoid signaling in both in vitro and in vivo models.