2,3-Dehydro-3,4-dihydro ivermectin
This ivermectin analog exhibits potent antileishmanial activity against both promastigote and amastigote forms of L. amazonensis, with IC50 values of 13.8 μM and 3.6 μM, respectively. It demonstrates a favorable selectivity index due to low cytotoxicity in macrophages (IC50 = 65.5 μM), supporting its investigation for in vitro and in vivo models of leishmaniasis.
Product Specifications
CAS Number
1135339-49-9
Field of Research
Infectious Disease & Virology
Smiles
CC[C@H] (C) [C@H]1O[C@]2 (CC[C@@H]1C) C[C@@H]1C[C@@H] (C\C=C (C) \[C@@H] (O[C@H]3C[C@H] (OC) [C@@H] (O[C@H]4C[C@H] (OC) [C@H] (O) [C@H] (C) O4) [C@H] (C) O3) [C@@H] (C) \C=C\C=C3/CO[C@@H]4[C@H] (O) C (C) C=C (C (=O) O1) [C@]34O) O2
Molecular Formula
C48H74O14
Molecular Weight
875.106
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
![Lymphocyte Activation Gene 3 (LAG3) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI8G6]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
TA807180AM 100 µL
Lymphocyte Activation Gene 3 (LAG3) Mouse Monoclonal Antibody (Biotin conjugated) [Clone ID: OTI8G6]
Sign In for Pricing
View Details 
44497156 3x 1.0 µg DNA
SNAP23 CRISPR All-in-one AAV vector set (with saCas9)(Rat)
Sign In for Pricing
View Details MBS1116579-01 0.02 mg (E-Coli)
Recombinant Yersinia pestis bv. Antiqua Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (accA)
Sign In for Pricing
View Details MBS1116579-02 0.02 mg (Yeast)
Recombinant Yersinia pestis bv. Antiqua Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (accA)
Sign In for Pricing
View Details MBS1116579-03 0.1 mg (E-Coli)
Recombinant Yersinia pestis bv. Antiqua Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (accA)
Sign In for Pricing
View Details MBS1116579-04 0.1 mg (Yeast)
Recombinant Yersinia pestis bv. Antiqua Acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha (accA)
Sign In for Pricing
View Details