Bismuth subcitrate (potassium)

Bismuth subcitrate potassium is a compound bismuth salt with oral activity. Bismuth subcitrate potassium has antibacterial activity and can inhibit the growth of Campylobacter pyloridis with a MIC50 of 8 μg/mL. Bismuth subcitrate potassium can be used in the study of gastrointestinal diseases infected by Campylobacter pyloridis[1][2][3].

Product Specifications

CAS Number

[880149-29-1]

UNSPSC

12352211

Target

Antibiotic; Bacterial

Type

Reference compound

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Assay Protocol

https://www.medchemexpress.com/bismuth-subcitrate-potassium.html

Purity

99.0

Solubility

H2O : 50 mg/mL (ultrasonic)

Smiles

O=C(O[Bi](OC(CC(C(O[K])=O)(O[K])CC(O[K])=O)=O)OC1=O)C(C1)(O[K])CC(O[K])=O

Molecular Formula

C12H8BiK5O14

Molecular Weight

780.66

References & Citations

[1]Van Caekenberghe DL, et al. In vitro synergistic activity between bismuth subcitrate and various antimicrobial agents against Campylobacter pyloridis (C. pylori) . Antimicrob Agents Chemother. 1987 Sep;31 (9) :1429-30.|[2]Malfertheiner P, et al. Helicobacter pylori eradication with a capsule containing bismuth subcitrate potassium, metronidazole, and tetracycline given with omeprazole versus clarithromycin-based triple therapy: a randomised, open-label, non-inferiority, phase 3 trial. Lancet. 2011 Mar 12;377 (9769) :905-13.|[3]Hussar DA. New drugs: retapamulin, bismuth subcitrate potassium, and rotigotine. J Am Pharm Assoc (2003) . 2007 Jul-Aug;47 (4) :539-43.