Meglutol
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis) . Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases[1][2].
Product Specifications
CAS Number
503-49-1
Product Name Alternative
Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid
UNSPSC
12352211
Hazard Statement
H315-H319
Target
Autophagy; Endogenous Metabolite; HMG-CoA Reductase (HMGCR)
Type
Natural Products
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Meglutol.html
Concentration
10mM
Purity
98.00
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)CC(C)(O)CC(O)=O
Molecular Formula
C6H10O5
Molecular Weight
162.14
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
Rabbit Anti PTK2 Polyclonal Affinity Purified (PBS with 0.02% sodium azide, 0.5% BSA and 50% glycerol, pH7.4) (Western Blot,IHC-p,Immunofluorescence,ELISA) 200ul
![Rabbit Polyclonal RYBP/DEDAF Antibody [PerCP]](https://cdn.genprice.uk/genprice/uk/genprice3.webp)
CDC42EP1, CT (CDC42EP1, BORG5, CEP1, MSE55, Cdc42 effector protein 1, Binder of Rho GTPases 5, Serum protein MSE55) (MaxLight 550)
CDC42EP1, CT (CDC42EP1, BORG5, CEP1, MSE55, Cdc42 effector protein 1, Binder of Rho GTPases 5, Serum protein MSE55) (MaxLight 550)