Meglutol
Meglutol is a lipid-lowering agent. Meglutol can reduces cholesterol, triglycerides, serum β-lipoprotein, and phospholipids, and inhibits the activity of HMG-CoA reductase (a rate-limiting enzyme in cholesterol biosynthesis) . Meglutol can induce significant lipid oxidative damage in brain tissue. It is promising for research in the field of cardiovascular diseases and metabolic diseases[1][2].
Product Specifications
CAS Number
[503-49-1]
Product Name Alternative
Dicrotalic acid; 3-Hydroxy-3-methylglutaric acid
UNSPSC
12352211
Hazard Statement
H315-H319
Target
Autophagy; Endogenous Metabolite; HMG-CoA Reductase (HMGCR)
Type
Natural Products
Related Pathways
Autophagy; Metabolic Enzyme/Protease
Applications
Neuroscience-Neuromodulation
Field of Research
Metabolic Disease; Cardiovascular Disease
Assay Protocol
https://www.medchemexpress.com/Meglutol.html
Concentration
10mM
Purity
98.00
Solubility
DMSO : 250 mg/mL (ultrasonic)
Smiles
O=C(O)CC(C)(O)CC(O)=O
Molecular Formula
C6H10O5
Molecular Weight
162.14
Precautions
P264-P280-P302+P352-P305+P351+P338-P362+P364
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Natural Products
Clinical Information
No Development Reported
Available Sizes
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