Δ7 (Z) -C14-HSL

Δ7 (Z) -C14-HSL (Compound 12) is an immunosuppressive agent that can inhibit the proliferation of mouse splenic cells with an IC50 of 17 μM. Δ7 (Z) -C14-HSL can be used for further studying its potential as a molecular mechanism in TNF-R-driven immune diseases, especially autoimmune diseases such as psoriasis, rheumatoid arthritis, and type 1 diabetes[1].

Product Specifications

CAS Number

[482598-46-9]

Product Name Alternative

N- (3-Oxo-7Z-tetradecenoyl) -L-homoserine lactone

UNSPSC

12352005

Hazard Statement

H225-H302+H312+H332-H319

Target

Others

Type

Reference compound

Related Pathways

Others

Applications

COVID-19-immunoregulation

Field of Research

Inflammation/Immunology

Assay Protocol

https://www.medchemexpress.com/7-z-c14-hsl.html

Solubility

10 mM in DMSO

Smiles

CCCCCC/C=C\CCCC(CC(N[C@@H]1C(OCC1)=O)=O)=O

Molecular Formula

C18H29NO4

Molecular Weight

323.43

Precautions

P210-P233-P240-P241-P242-P243-P261-P264-P270-P271-P280-P302+P352-P303+P361+P353-P304+P340-P305+P351+P338-P330-P362+P364-P370+P378-P403+P235-P501

References & Citations

[1]Chhabra SR, et al. Synthetic analogues of the bacterial signal (quorum sensing) molecule N- (3-oxododecanoyl) -L-homoserine lactone as immune modulators. J Med Chem. 2003 Jan 2;46 (1) :97-104.