MC-betaglucuronide-MMAE-1
MC-betaglucuronide-MMAE-1 is a cleavable linker-drug conjugate for constructing antibody-drug conjugates (ADCs) . Its payload, MMAE, inhibits tubulin polymerization, enabling potent antitumor activity. This conjugate is utilized in ADC research for both in vitro cytotoxicity assays and in vivo efficacy studies in preclinical cancer models.
Product Specifications
CAS Number
1703778-92-0
Smiles
CC[C@H] (C) [C@@H] ([C@@H] (CC (=O) N1CCC[C@H]1[C@H] (OC) [C@@H] (C) C (=O) N[C@H] (C) [C@@H] (O) c1ccccc1) OC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) OCc1ccc (O[C@@H]2O[C@@H] ([C@@H] (O) [C@H] (O) [C@H]2O) C (O) =O) c (NC (=O) CCNC (=O) CCCCCN2C (=O) C=CC2=O) c1) C (C) C
Molecular Formula
C66H98N8O20
Molecular Weight
1323.546
Storage Conditions
-20°C
Notes
For research use only.
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