Azido-PEG4-Val-Cit-PAB-MMAE
This ADC drug-linker conjugate features the potent tubulin inhibitor MMAE connected via a cleavable Azido-PEG4-Val-Cit-PAB linker. It is widely used in research for constructing antibody-drug conjugates to evaluate targeted cytotoxicity in both in vitro cell assays and in vivo xenograft models.
Product Specifications
CAS Number
1869126-64-6
Field of Research
Signal Transduction
Smiles
[H][C@]1 (CCCN1C (=O) C[C@@H] (OC) [C@H] ([C@@H] (C) CC) N (C) C (=O) [C@@H] (NC (=O) [C@H] (C (C) C) N (C) C (=O) OCc1ccc (NC (=O) [C@H] (CCCNC (N) =O) NC (=O) [C@@H] (NC (=O) CCOCCOCCOCCOCCN=[N+]=[N-]) C (C) C) cc1) C (C) C) [C@H] (OC) [C@@H] (C) C (=O) N[C@H] (C) [C@@H] (O) c1ccccc1
Molecular Formula
C69H113N13O17
Molecular Weight
1396.737
Storage Conditions
-20°C
Notes
For research use only.
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