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PROTAC IRAK4 degrader-4

PROTAC IRAK4 degrader-4 (compound I-127) is a cereblon-recruiting heterobifunctional degrader designed for the targeted protein degradation of IRAK4. This tool compound is used in preclinical research to investigate IRAK4's role in inflammation and oncology, with studies demonstrating its activity in both cellular and in vivo models.

Product Specifications

CAS Number

2360528-45-4

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Smiles

NC (=O) c1nn (cc1NC (=O) c1coc (n1) -c1ccnc (NCC (F) (F) F) c1) -c1ccc (cc1) C (=O) NCCOCCOCCNc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12

Molecular Formula

C41H38F3N11O10

Molecular Weight

901.817

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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