PROTAC IRAK4 degrader-4
PROTAC IRAK4 degrader-4 (compound I-127) is a cereblon-recruiting heterobifunctional degrader designed for the targeted protein degradation of IRAK4. This tool compound is used in preclinical research to investigate IRAK4's role in inflammation and oncology, with studies demonstrating its activity in both cellular and in vivo models.
Product Specifications
CAS Number
2360528-45-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
NC (=O) c1nn (cc1NC (=O) c1coc (n1) -c1ccnc (NCC (F) (F) F) c1) -c1ccc (cc1) C (=O) NCCOCCOCCNc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C41H38F3N11O10
Molecular Weight
901.817
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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