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PROTAC IRAK4 degrader-5

PROTAC IRAK4 degrader-5 is a heterobifunctional small molecule that utilizes the Cereblon E3 ligase to selectively degrade IRAK4. This tool compound is used in vitro and in vivo to investigate IRAK4's role in oncology and autoimmune disease research, particularly in the context of MYD88-mutant lymphomas.

Product Specifications

CAS Number

2360530-61-4

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction

Smiles

NC (=O) c1nn (cc1NC (=O) c1coc (n1) -c1ccnc (NCC (F) (F) F) c1) -c1ccc (CNCCOCCOCCNc2cccc3C (=O) N (C4CCC (=O) NC4=O) C (=O) c23) cc1

Molecular Formula

C41H40F3N11O9

Molecular Weight

887.834

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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