PROTAC IRAK4 degrader-5
PROTAC IRAK4 degrader-5 is a heterobifunctional small molecule that utilizes the Cereblon E3 ligase to selectively degrade IRAK4. This tool compound is used in vitro and in vivo to investigate IRAK4's role in oncology and autoimmune disease research, particularly in the context of MYD88-mutant lymphomas.
Product Specifications
CAS Number
2360530-61-4
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery, Signal Transduction
Smiles
NC (=O) c1nn (cc1NC (=O) c1coc (n1) -c1ccnc (NCC (F) (F) F) c1) -c1ccc (CNCCOCCOCCNc2cccc3C (=O) N (C4CCC (=O) NC4=O) C (=O) c23) cc1
Molecular Formula
C41H40F3N11O9
Molecular Weight
887.834
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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