Thalidomide-PEG4-NH2 hydrochloride
Thalidomide-PEG4-NH2 hydrochloride is a cereblon (CRBN) -directed E3 ligase ligand-linker conjugate, widely used in PROTAC development for targeted protein degradation. This compound serves as a key building block for constructing PROTAC molecules in both in vitro biochemical assays and in vivo preclinical research.
Product Specifications
CAS Number
2387510-82-7
Field of Research
Cell Biology, Pharmacology & Drug Discovery
Smiles
Cl.NCCOCCOCCOCCOc1cccc2C (=O) N (C3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C21H28ClN3O8
Molecular Weight
485.92
Storage Conditions
-20°C
Notes
For research use only.
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