PROTAC BRD4 Degrader-15
PROTAC BRD4 Degrader-15 is a heterobifunctional degrader that recruits the VHL E3 ligase to BRD4, inducing its proteasomal degradation. It potently degrades BRD4 in PC3 prostate cancer cells and is a valuable chemical tool for studying BRD4 biology and targeted protein degradation in oncology research.
Product Specifications
CAS Number
2417370-67-1
Field of Research
Epigenetics & Chromatin, Pharmacology & Drug Discovery
Smiles
Cc1ncsc1-c1ccc (CNC (=O) [C@@H]2C[C@@H] (O) CN2C (=O) [C@@H] (NC (=O) COCCc2cc (N) cc (OCCNC (=O) c3cc4N (Cc5c[nH]c6c5c (cn (C) c6=O) -c4cc3CS (C) (=O) =O) c3ncc (F) cc3F) c2) C (C) (C) C) cc1 |@@:75|
Molecular Formula
C57H62F2N10O10S2
Molecular Weight
1149.3
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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