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RM-018

RM-018 is a potent and selective tricomplex inhibitor targeting the active state of KRAS G12C. Its unique mechanism enables inhibition of both wild-type and resistant KRAS G12C/Y96D mutants, supporting its use in in vitro biochemical assays and in vivo efficacy studies for oncology research.

Product Specifications

CAS Number

2641993-55-5

Field of Research

Pharmacology & Drug Discovery, Signal Transduction

Smiles

CCn1c (c2CC (C) (C) COC (=O) [C@@H]3CCCN (N3) C (=O) [C@H] (Cc3cccc (c3) -c3ccc1c2c3) NC (=O) [C@H] (C (C) C) N (C) C (=O) [C@H]1CCN (C1) C (=O) C#CCN1CCOCC1) -c1cccnc1[C@H] (C) OC

Molecular Formula

C56H72N8O8

Molecular Weight

985.24

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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