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P21d hydrochloride

P21d hydrochloride is a potent, selective Brk inhibitor (IC50 = 30 nM) with over 650-fold selectivity against Aurora B and Lck. It downregulates SNAIL, restores E-cadherin, and suppresses breast cancer cell migration. This orally bioavailable compound is active in both cellular assays and in vivo models for studying metastasis and EMT.

Product Specifications

Storage Conditions

-20°C

Notes

For research use only.

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