Cimiside E
Cimiside E exhibits anti-inflammatory activity by selectively inhibiting TNF-α-induced VCAM-1 expression, an effect mediated through PPAR-γ upregulation and involving ERK1/2, PI3K, and PKC signaling. It also demonstrates potential chemopreventive properties against gastric cancer by inducing cell cycle arrest and apoptosis in vitro.
Product Specifications
CAS Number
154822-57-8
Field of Research
Cell Biology, Epigenetics & Chromatin, Immunology & Inflammation, Metabolism Research, Molecular Biology, Protein Biochemistry, Signal Transduction
Smiles
[H][C@]12[C@H] (C) C[C@H]3O[C@@]1 (O[C@H]3C (C) =C) [C@H] (O) [C@@]1 (C) [C@]3 ([H]) CC[C@]4 ([H]) [C@]5 (C[C@@]35CC[C@]21C) CC[C@H] (O[C@@H]1OC[C@@H] (O) [C@H] (O) [C@H]1O) C4 (C) C
Molecular Formula
C35H54O8
Molecular Weight
602.809
Storage Conditions
-20°C
Notes
For research use only.
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