Graveoline
Graveoline (Rutamine) is an orally active alkaloid with various activities such as antifungal, antiparasitic, anti-inflammatory, and antitumor effects. Graveoline can induce tumor cell apoptosis and autophagy through a reactive oxygen species-mediated pathway. Graveoline has an MIC of 500 μg/mL for Candida albicans. Graveoline can be used in the research of various diseases such as tumors and liver injury[1][2][3][4].
Product Specifications
CAS Number
485-61-0
Product Name Alternative
Rutamine
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
Apoptosis; Autophagy; Fungal; Interleukin Related; JAK; Parasite; Reactive Oxygen Species (ROS) ; STAT
Type
Reference compound
Related Pathways
Applications
COVID-19-immunoregulation
Field of Research
Cancer; Infection; Inflammation/Immunology
Assay Protocol
https://www.medchemexpress.com/graveoline.html
Concentration
10mM
Purity
99.88
Solubility
DMSO : 20 mg/mL (ultrasonic; warming; heat to 60°C)
Smiles
O=C1C=C(C2=CC=C(OCO3)C3=C2)N(C)C4=C1C=CC=C4
Molecular Formula
C17H13NO3
Molecular Weight
279.30
Precautions
H302, H315, H319, H335
References & Citations
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
IL-10; IL-4; JAK1; STAT3
Available Sizes
Frequently Asked Questions
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