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Gefitinib N-oxide hydrochloride

Gefitinib N-oxide hydrochloride is a potent EGFR tyrosine kinase inhibitor, demonstrating activity in the low nanomolar range (IC50 2-37 nM) in cellular assays. This compound is a key metabolite for research into EGFR-driven pathologies, useful in both in vitro and in vivo studies to investigate resistance mechanisms and therapeutic efficacy.

Product Specifications

Field of Research

Cardiovascular Research, Pharmacology & Drug Discovery, Signal Transduction

Molecular Formula

C22H24ClFN4O41.5HCl

Molecular Weight

517.59

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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