Dot1L-IN-1 TFA
Dot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with sub-nanomolar activity. It effectively reduces H3K79 dimethylation and suppresses HoxA9 promoter activity in cellular assays, making it a valuable chemical probe for epigenetic research in oncology and hematology, including studies of MLL-rearranged leukemia.
Product Specifications
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation; Epigenetics & Chromatin
Molecular Formula
C34H37ClF3N9O4S
Molecular Weight
760.23
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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