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Dot1L-IN-1 TFA

Dot1L-IN-1 TFA is a highly potent and selective Dot1L inhibitor with sub-nanomolar activity. It effectively reduces H3K79 dimethylation and suppresses HoxA9 promoter activity in cellular assays, making it a valuable chemical probe for epigenetic research in oncology and hematology, including studies of MLL-rearranged leukemia.

Product Specifications

Field of Research

Epigenetics & Chromatin, Immunology & Inflammation; Epigenetics & Chromatin

Molecular Formula

C34H37ClF3N9O4S

Molecular Weight

760.23

Storage Conditions

-20°C

Notes

For research use only.

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