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Thiomarinol A

Thiomarinol A (4-Hydroxythiomarinol C) is a potent hybrid antibiotic combining dithiolopyrrolone and marinolic acid scaffolds. It acts as a dose-dependent inhibitor of MRSA isoleucyl-tRNA synthetase (IleRS) with a K_i of 19 nM, showing promise for in vitro studies of novel antimicrobial mechanisms against drug-resistant bacteria.

Product Specifications

CAS Number

146697-04-3

Field of Research

Infectious Disease & Virology

Smiles

[H][C@]1 (OC[C@H] (C\C=C\[C@@H] (C) [C@H] (C) O) [C@@H] (O) [C@H]1O) [C@H] (O) C (\C) =C\C (=O) OCCCCCCCC (=O) Nc1c2sscc2[nH]c1=O

Molecular Formula

C30H44N2O9S2

Molecular Weight

640.81

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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