Thiomarinol A
Thiomarinol A (4-Hydroxythiomarinol C) is a potent hybrid antibiotic combining dithiolopyrrolone and marinolic acid scaffolds. It acts as a dose-dependent inhibitor of MRSA isoleucyl-tRNA synthetase (IleRS) with a K_i of 19 nM, showing promise for in vitro studies of novel antimicrobial mechanisms against drug-resistant bacteria.
Product Specifications
CAS Number
146697-04-3
Field of Research
Infectious Disease & Virology
Smiles
[H][C@]1 (OC[C@H] (C\C=C\[C@@H] (C) [C@H] (C) O) [C@@H] (O) [C@H]1O) [C@H] (O) C (\C) =C\C (=O) OCCCCCCCC (=O) Nc1c2sscc2[nH]c1=O
Molecular Formula
C30H44N2O9S2
Molecular Weight
640.81
Storage Conditions
-20°C
Notes
For research use only.
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