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SR 142948 dihydrochloride

SR 142948 dihydrochloride is a potent, brain-penetrant, and selective non-peptide antagonist of the neurotensin receptor (NTR1) . It effectively blocks neurotensin-mediated signaling in cellular assays (e.g., inositol monophosphate formation in HT-29 cells) and inhibits NT-induced behavioral responses like hypothermia and analgesia in vivo, making it a valuable research tool for studying psychiatric and neurological disorders.

Product Specifications

Field of Research

Pharmacology & Drug Discovery

Molecular Formula

C39H53Cl2N5O6

Molecular Weight

758.77

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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