Prostaglandin J2
Prostaglandin J2 (PGJ2) is a potent DP receptor agonist derived from PGD2, with high affinity for hDP (Ki=0.9 nM) and hCRTH2 receptors. It induces cAMP production, oxidative stress, and neuronal apoptosis, making it a critical tool for studying neurotoxic mechanisms in Alzheimer's and Parkinson's disease models in vitro.
Product Specifications
CAS Number
60203-57-8
Field of Research
Immunology & Inflammation, Metabolism Research, Pharmacology & Drug Discovery
Smiles
CCCCC[C@H] (O) \C=C\[C@@H]1[C@@H] (C\C=C/CCCC (O) =O) C=CC1=O
Molecular Formula
C20H30O4
Molecular Weight
334.45
Storage Conditions
-20°C
Notes
For research use only.
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