SLF TFA
SLF TFA is a synthetic FKBP ligand with a 3.1 μM affinity for FKBP51 and a 2.6 μM IC50 for FKBP12. It is widely used as a key recruiting element in PROTAC synthesis for targeted protein degradation research in both cellular and in vivo models.
Product Specifications
CAS Number
2378802-47-0
Field of Research
Cell Biology, Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
C (C (O) =O) (F) (F) F.C (C (C (CC) (C) C) =O) (=O) N1[C@H] (C (O[C@H] (CCC2=CC (OC) =C (OC) C=C2) C3=CC (N) =CC=C3) =O) CCCC1
Molecular Formula
C32H41F3N2O8
Molecular Weight
638.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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