PF-06456384 trihydrochloride
PF-06456384 trihydrochloride is a potent and selective NaV1.7 inhibitor with an IC50 of 0.01 nM, functioning via direct protein-ligand binding. Designed for intravenous administration, it serves as a valuable research tool for investigating pain mechanisms in both in vitro and in vivo models.
Product Specifications
CAS Number
1834610-75-1
Product Name Alternative
PF06456384 trihydrochloride
Field of Research
Pharmacology & Drug Discovery
Purity
99.16% (May vary between batches)
Solubility
DMSO:100 mg/mL (120.6 mM)
Smiles
N#CC1=CC (S (=O) (NC2=NC=NS2) =O) =CC=C1OC3=CC=C (C4=CC (C (F) (F) F) =CC=C4) C=C3C5=CC (CNCCC6CCNCC6) =NC=C5.Cl.Cl.Cl
Molecular Formula
C35H35Cl3F3N7O3S2
Molecular Weight
829.18
Storage Conditions
-20°C
Notes
For research use only.
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