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BCL6 PROTAC 1

BCL6 PROTAC 1 is a potent and selective degrader of the BCL6 protein, demonstrating an IC50 of 8.8 μM in cellular reporter assays and effective degradation in DLBCL cell lines. This tool compound is valuable for investigating BCL6-dependent oncogenic mechanisms in hematological cancers, supporting both in vitro and in vivo tumor biology research.

Product Specifications

CAS Number

2257479-54-0

Field of Research

Immunology & Inflammation, Pharmacology & Drug Discovery

Smiles

[H][C@]12CN (CCN1c1ncc (Cl) c (Nc3cc4CCC (=O) N (C) c4c (OCCOC2) c3) n1) C (=O) CCC (=O) NCCCOCCOCCOc1cccc2C (=O) N ([C@H]3CCC (=O) NC3=O) C (=O) c12

Molecular Formula

C45H52ClN9O12

Molecular Weight

946.4

Storage Conditions

-20°C

Notes

For research use only.

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