BCL6 PROTAC 1
BCL6 PROTAC 1 is a potent and selective degrader of the BCL6 protein, demonstrating an IC50 of 8.8 μM in cellular reporter assays and effective degradation in DLBCL cell lines. This tool compound is valuable for investigating BCL6-dependent oncogenic mechanisms in hematological cancers, supporting both in vitro and in vivo tumor biology research.
Product Specifications
CAS Number
2257479-54-0
Field of Research
Immunology & Inflammation, Pharmacology & Drug Discovery
Smiles
[H][C@]12CN (CCN1c1ncc (Cl) c (Nc3cc4CCC (=O) N (C) c4c (OCCOC2) c3) n1) C (=O) CCC (=O) NCCCOCCOCCOc1cccc2C (=O) N ([C@H]3CCC (=O) NC3=O) C (=O) c12
Molecular Formula
C45H52ClN9O12
Molecular Weight
946.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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