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Sanggenon G

Sanggenon G is a cell-permeable small molecule that potently inhibits XIAP by binding to its BIR3 domain with 34.26 μM affinity, promoting caspase activation. This compound is a useful research tool for studying apoptosis mechanisms and has been employed in both in vitro and in vivo cancer research models to investigate sensitization to cell death.

Product Specifications

CAS Number

85698-31-3

Field of Research

Cell Biology, Protein Biochemistry

Smiles

CC (C) =CCCC1=C[C@@H] ([C@H] ([C@@H] (C1) c1ccc (O) cc1O) C (=O) c1ccc (O) cc1O) c1c (O) cc2O[C@@H] (CC (=O) c2c1O) c1ccc (O) cc1O

Molecular Formula

C40H38O11

Molecular Weight

694.72

Storage Conditions

-20°C

Notes

For research use only.

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