Sanggenon G
Sanggenon G is a cell-permeable small molecule that potently inhibits XIAP by binding to its BIR3 domain with 34.26 μM affinity, promoting caspase activation. This compound is a useful research tool for studying apoptosis mechanisms and has been employed in both in vitro and in vivo cancer research models to investigate sensitization to cell death.
Product Specifications
CAS Number
85698-31-3
Field of Research
Cell Biology, Protein Biochemistry
Smiles
CC (C) =CCCC1=C[C@@H] ([C@H] ([C@@H] (C1) c1ccc (O) cc1O) C (=O) c1ccc (O) cc1O) c1c (O) cc2O[C@@H] (CC (=O) c2c1O) c1ccc (O) cc1O
Molecular Formula
C40H38O11
Molecular Weight
694.72
Storage Conditions
-20°C
Notes
For research use only.
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