AB-680 ammonium

AB-680 ammonium is a highly potent and selective inhibitor of human CD73 (ecto-5'-nucleotidase), with a Ki of 4.9 pM and >10,000-fold selectivity over CD39. This small molecule is a valuable research tool for investigating adenosine-mediated immunosuppression in oncology, demonstrating anti-tumor efficacy in both cellular assays and in vivo models.