SN-38 glucuronide
SN-38 glucuronide is the inactive, detoxified metabolite of the topoisomerase I inhibitor Irinotecan. This derivative is a key research tool for studying the pharmacokinetics, toxicity, and reactivation mechanisms of Irinotecan in models of colorectal cancer, both in vitro and in vivo.
Product Specifications
CAS Number
121080-63-5
Field of Research
Metabolism Research
Smiles
CCc1c2Cn3c (cc4c (COC (=O) [C@]4 (O) CC) c3=O) -c2nc2ccc (O[C@@H]3O[C@@H] ([C@@H] (O) [C@H] (O) [C@H]3O) C (O) =O) cc12
Molecular Formula
C28H28N2O11
Molecular Weight
568.53
Storage Conditions
-20°C
Notes
For research use only.
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