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Ep300/CREBBP-IN-2

Ep300/CREBBP-IN-2 (Example 73) is a potent, orally bioavailable dual inhibitor of Ep300 and CREBBP with IC50 values of 0.052 μM and 0.148 μM, respectively. It is widely used in cancer research to investigate the roles of these acetyltransferases in tumorigenesis, both in cellular and animal models.

Product Specifications

CAS Number

2259641-59-1

Field of Research

Epigenetics & Chromatin, Signal Transduction

Smiles

COc1ccc (cc1) C1 (CCC (F) (F) CC1) C (=O) N1C[C@H] (F) C[C@@H]1C (=O) Nc1ccc2NC (=O) Cc2n1

Molecular Formula

C26H27F3N4O4

Molecular Weight

516.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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